| W1 | SEP 4, 2025 |  Philadelphia EaglesDallas Cowboys @ Philadelphia Eagles | Away | 20 - 24 | Final | Open |
| W2 | SEP 14, 2025 |  New York GiantsNew York Giants @ Dallas Cowboys | Home | 37 - 40 | Final | Open |
| W3 | SEP 21, 2025 |  Chicago BearsDallas Cowboys @ Chicago Bears | Away | 14 - 31 | Final | Open |
| W4 | SEP 28, 2025 |  Green Bay PackersGreen Bay Packers @ Dallas Cowboys | Home | 40 - 40 | Final | Open |
| W5 | OCT 5, 2025 |  New York JetsDallas Cowboys @ New York Jets | Away | 37 - 22 | Final | Open |
| W6 | OCT 12, 2025 |  Carolina PanthersDallas Cowboys @ Carolina Panthers | Away | 27 - 30 | Final | Open |
| W7 | OCT 19, 2025 |  Washington CommandersWashington Commanders @ Dallas Cowboys | Home | 22 - 44 | Final | Open |
| W8 | OCT 26, 2025 |  Denver BroncosDallas Cowboys @ Denver Broncos | Away | 24 - 44 | Final | Open |
| W9 | NOV 3, 2025 |  Arizona CardinalsArizona Cardinals @ Dallas Cowboys | Home | 27 - 17 | Final | Open |
| W10 | - | ByeDallas Cowboys Bye Week | - | - | Bye | Rest |
| W11 | NOV 17, 2025 |  Las Vegas RaidersDallas Cowboys @ Las Vegas Raiders | Away | 33 - 16 | Final | Open |
| W12 | NOV 23, 2025 | Philadelphia EaglesPhiladelphia Eagles @ Dallas Cowboys | Home | 21 - 24 | Final | Open |
| W13 | NOV 27, 2025 |  Kansas City ChiefsKansas City Chiefs @ Dallas Cowboys | Home | 28 - 31 | Final | Open |
| W14 | DEC 4, 2025 |  Detroit LionsDallas Cowboys @ Detroit Lions | Away | 30 - 44 | Final | Open |
| W15 | DEC 14, 2025 |  Minnesota VikingsMinnesota Vikings @ Dallas Cowboys | Home | 34 - 26 | Final | Open |
| W16 | DEC 21, 2025 |  Los Angeles ChargersLos Angeles Chargers @ Dallas Cowboys | Home | 34 - 17 | Final | Open |
| W17 | DEC 25, 2025 | Washington CommandersDallas Cowboys @ Washington Commanders | Away | 30 - 23 | Final | Open |
| W18 | JAN 4, 2026 | New York GiantsDallas Cowboys @ New York Giants | Away | 17 - 34 | Final | Open |
