| W1 | SEP 7, 2025 |  Cleveland BrownsCincinnati Bengals @ Cleveland Browns | Away | 17 - 16 | Final | Open |
| W2 | SEP 14, 2025 |  Jacksonville JaguarsJacksonville Jaguars @ Cincinnati Bengals | Home | 27 - 31 | Final | Open |
| W3 | SEP 21, 2025 |  Minnesota VikingsCincinnati Bengals @ Minnesota Vikings | Away | 10 - 48 | Final | Open |
| W4 | SEP 29, 2025 |  Denver BroncosCincinnati Bengals @ Denver Broncos | Away | 3 - 28 | Final | Open |
| W5 | OCT 5, 2025 |  Detroit LionsDetroit Lions @ Cincinnati Bengals | Home | 37 - 24 | Final | Open |
| W6 | OCT 12, 2025 |  Green Bay PackersCincinnati Bengals @ Green Bay Packers | Away | 18 - 27 | Final | Open |
| W7 | OCT 16, 2025 |  Pittsburgh SteelersPittsburgh Steelers @ Cincinnati Bengals | Home | 31 - 33 | Final | Open |
| W8 | OCT 26, 2025 |  New York JetsNew York Jets @ Cincinnati Bengals | Home | 39 - 38 | Final | Open |
| W9 | NOV 2, 2025 |  Chicago BearsChicago Bears @ Cincinnati Bengals | Home | 47 - 42 | Final | Open |
| W10 | - | ByeCincinnati Bengals Bye Week | - | - | Bye | Rest |
| W11 | NOV 16, 2025 | Pittsburgh SteelersCincinnati Bengals @ Pittsburgh Steelers | Away | 12 - 34 | Final | Open |
| W12 | NOV 23, 2025 |  New England PatriotsNew England Patriots @ Cincinnati Bengals | Home | 26 - 20 | Final | Open |
| W13 | NOV 27, 2025 |  Baltimore RavensCincinnati Bengals @ Baltimore Ravens | Away | 32 - 14 | Final | Open |
| W14 | DEC 7, 2025 |  Buffalo BillsCincinnati Bengals @ Buffalo Bills | Away | 34 - 39 | Final | Open |
| W15 | DEC 14, 2025 | Baltimore RavensBaltimore Ravens @ Cincinnati Bengals | Home | 24 - 0 | Final | Open |
| W16 | DEC 21, 2025 |  Miami DolphinsCincinnati Bengals @ Miami Dolphins | Away | 45 - 21 | Final | Open |
| W17 | DEC 28, 2025 |  Arizona CardinalsArizona Cardinals @ Cincinnati Bengals | Home | 14 - 37 | Final | Open |
| W18 | JAN 4, 2026 | Cleveland BrownsCleveland Browns @ Cincinnati Bengals | Home | 20 - 18 | Final | Open |
