| W1 | SEP 7, 2025 |  Indianapolis ColtsMiami Dolphins @ Indianapolis Colts | Away | 8 - 33 | Final | Open |
| W2 | SEP 14, 2025 |  New England PatriotsNew England Patriots @ Miami Dolphins | Home | 33 - 27 | Final | Open |
| W3 | SEP 18, 2025 |  Buffalo BillsMiami Dolphins @ Buffalo Bills | Away | 21 - 31 | Final | Open |
| W4 | SEP 29, 2025 |  New York JetsNew York Jets @ Miami Dolphins | Home | 21 - 27 | Final | Open |
| W5 | OCT 5, 2025 |  Carolina PanthersMiami Dolphins @ Carolina Panthers | Away | 24 - 27 | Final | Open |
| W6 | OCT 12, 2025 |  Los Angeles ChargersLos Angeles Chargers @ Miami Dolphins | Home | 29 - 27 | Final | Open |
| W7 | OCT 19, 2025 |  Cleveland BrownsMiami Dolphins @ Cleveland Browns | Away | 6 - 31 | Final | Open |
| W8 | OCT 26, 2025 |  Atlanta FalconsMiami Dolphins @ Atlanta Falcons | Away | 34 - 10 | Final | Open |
| W9 | OCT 30, 2025 |  Baltimore RavensBaltimore Ravens @ Miami Dolphins | Home | 28 - 6 | Final | Open |
| W10 | NOV 9, 2025 | Buffalo BillsBuffalo Bills @ Miami Dolphins | Home | 13 - 30 | Final | Open |
| W11 | NOV 16, 2025 |  Washington CommandersWashington Commanders @ Miami Dolphins | Home | 13 - 16 | Final | Open |
| W12 | - | ByeMiami Dolphins Bye Week | - | - | Bye | Rest |
| W13 | NOV 30, 2025 |  New Orleans SaintsNew Orleans Saints @ Miami Dolphins | Home | 17 - 21 | Final | Open |
| W14 | DEC 7, 2025 | New York JetsMiami Dolphins @ New York Jets | Away | 34 - 10 | Final | Open |
| W15 | DEC 15, 2025 |  Pittsburgh SteelersMiami Dolphins @ Pittsburgh Steelers | Away | 15 - 28 | Final | Open |
| W16 | DEC 21, 2025 |  Cincinnati BengalsCincinnati Bengals @ Miami Dolphins | Home | 45 - 21 | Final | Open |
| W17 | DEC 28, 2025 |  Tampa Bay BuccaneersTampa Bay Buccaneers @ Miami Dolphins | Home | 17 - 20 | Final | Open |
| W18 | JAN 4, 2026 | New England PatriotsMiami Dolphins @ New England Patriots | Away | 10 - 38 | Final | Open |
