| W1 | SEP 7, 2025 |  Tampa Bay BuccaneersTampa Bay Buccaneers @ Atlanta Falcons | Home | 23 - 20 | Final | Open |
| W2 | SEP 14, 2025 |  Minnesota VikingsAtlanta Falcons @ Minnesota Vikings | Away | 22 - 6 | Final | Open |
| W3 | SEP 21, 2025 |  Carolina PanthersAtlanta Falcons @ Carolina Panthers | Away | 0 - 30 | Final | Open |
| W4 | SEP 28, 2025 |  Washington CommandersWashington Commanders @ Atlanta Falcons | Home | 27 - 34 | Final | Open |
| W5 | - | ByeAtlanta Falcons Bye Week | - | - | Bye | Rest |
| W6 | OCT 13, 2025 |  Buffalo BillsBuffalo Bills @ Atlanta Falcons | Home | 14 - 24 | Final | Open |
| W7 | OCT 19, 2025 |  San Francisco 49ersAtlanta Falcons @ San Francisco 49ers | Away | 10 - 20 | Final | Open |
| W8 | OCT 26, 2025 |  Miami DolphinsMiami Dolphins @ Atlanta Falcons | Home | 34 - 10 | Final | Open |
| W9 | NOV 2, 2025 |  New England PatriotsAtlanta Falcons @ New England Patriots | Away | 23 - 24 | Final | Open |
| W10 | NOV 9, 2025 |  Indianapolis ColtsAtlanta Falcons @ Indianapolis Colts | Away | 25 - 31 | Final | Open |
| W11 | NOV 16, 2025 | Carolina PanthersCarolina Panthers @ Atlanta Falcons | Home | 30 - 27 | Final | Open |
| W12 | NOV 23, 2025 |  New Orleans SaintsAtlanta Falcons @ New Orleans Saints | Away | 24 - 10 | Final | Open |
| W13 | NOV 30, 2025 |  New York JetsAtlanta Falcons @ New York Jets | Away | 24 - 27 | Final | Open |
| W14 | DEC 7, 2025 |  Seattle SeahawksSeattle Seahawks @ Atlanta Falcons | Home | 37 - 9 | Final | Open |
| W15 | DEC 11, 2025 | Tampa Bay BuccaneersAtlanta Falcons @ Tampa Bay Buccaneers | Away | 29 - 28 | Final | Open |
| W16 | DEC 21, 2025 |  Arizona CardinalsAtlanta Falcons @ Arizona Cardinals | Away | 26 - 19 | Final | Open |
| W17 | DEC 29, 2025 |  Los Angeles RamsLos Angeles Rams @ Atlanta Falcons | Home | 24 - 27 | Final | Open |
| W18 | JAN 4, 2026 | New Orleans SaintsNew Orleans Saints @ Atlanta Falcons | Home | 17 - 19 | Final | Open |
