| W1 | SEP 7, 2025 |  New England PatriotsLas Vegas Raiders @ New England Patriots | Away | 20 - 13 | Final | Open |
| W2 | SEP 15, 2025 |  Los Angeles ChargersLos Angeles Chargers @ Las Vegas Raiders | Home | 20 - 9 | Final | Open |
| W3 | SEP 21, 2025 |  Washington CommandersLas Vegas Raiders @ Washington Commanders | Away | 24 - 41 | Final | Open |
| W4 | SEP 28, 2025 |  Chicago BearsChicago Bears @ Las Vegas Raiders | Home | 25 - 24 | Final | Open |
| W5 | OCT 5, 2025 |  Indianapolis ColtsLas Vegas Raiders @ Indianapolis Colts | Away | 6 - 40 | Final | Open |
| W6 | OCT 12, 2025 |  Tennessee TitansTennessee Titans @ Las Vegas Raiders | Home | 10 - 20 | Final | Open |
| W7 | OCT 19, 2025 |  Kansas City ChiefsLas Vegas Raiders @ Kansas City Chiefs | Away | 0 - 31 | Final | Open |
| W8 | - | ByeLas Vegas Raiders Bye Week | - | - | Bye | Rest |
| W9 | NOV 2, 2025 |  Jacksonville JaguarsJacksonville Jaguars @ Las Vegas Raiders | Home | 30 - 29 | Final | Open |
| W10 | NOV 6, 2025 |  Denver BroncosLas Vegas Raiders @ Denver Broncos | Away | 7 - 10 | Final | Open |
| W11 | NOV 17, 2025 |  Dallas CowboysDallas Cowboys @ Las Vegas Raiders | Home | 33 - 16 | Final | Open |
| W12 | NOV 23, 2025 |  Cleveland BrownsCleveland Browns @ Las Vegas Raiders | Home | 24 - 10 | Final | Open |
| W13 | NOV 30, 2025 | Los Angeles ChargersLas Vegas Raiders @ Los Angeles Chargers | Away | 14 - 31 | Final | Open |
| W14 | DEC 7, 2025 | Denver BroncosDenver Broncos @ Las Vegas Raiders | Home | 24 - 17 | Final | Open |
| W15 | DEC 14, 2025 |  Philadelphia EaglesLas Vegas Raiders @ Philadelphia Eagles | Away | 0 - 31 | Final | Open |
| W16 | DEC 21, 2025 |  Houston TexansLas Vegas Raiders @ Houston Texans | Away | 21 - 23 | Final | Open |
| W17 | DEC 28, 2025 |  New York GiantsNew York Giants @ Las Vegas Raiders | Home | 34 - 10 | Final | Open |
| W18 | JAN 4, 2026 | Kansas City ChiefsKansas City Chiefs @ Las Vegas Raiders | Home | 12 - 14 | Final | Open |
